Measuring Pharmacodynamics: From Ligand Binding to Clinical Outcomes
About this course
Drugs are biologically active compounds. Drug discovery and drug development rely on methods for measuring biological activity. The term “activity” is quite general. In practice, a substance’s biological activity can refer to how a substance affects a biological pathway, cell-level responses, safety risks, how long a substance resides within in a system, as well as a substance’s effects in an organism (called pharmacodynamics). The design of methods for measuring activity is a critical aspect of drug discovery. The design of robust and informative methods can accelerate the drug discovery and development process.
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What you'll learn
- understand the concept of pharmacodynamics
- measure biological activity of substances
- design robust methods for measuring drug activity
Course objectives
- provide an overview of drug discovery and development
- explain key concepts in pharmacodynamics
- introduce methods for measuring biological activity
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